| Seiyuu | Role |
| Masakazu Morita | Ichigo Kurosaki |
| Fumiko Orikasa | Rukia Kuchiki |
| Yuki Matsuoka | Orihime Inoue |
| Noriaki Sugiyama | Uryuu Ishida |
| Toshiyuki Morikawa | Isshin Kurosaki (Ichigo's Father) |
| Junko Noda | Tatsuki Arisawa |
| Rie Kugimiya | Karin Kurosaki |
| Shinichirou Miki | Kisuke Urahara |
| Mitsuaki Madono | Kon |
| Hiroki Yasumoto | Yasutora Sado (Chad) |
| Tomoe Sakuragawa | Yuzu Kurosaki |
| Kouji Yusa | Gin Ichimaru |
| Jun Fukuyama | Mizuiro Kojima |
| Katsuyuki Konishi | Keigo Asano |
| Kentarou Itou | Renji Abarai |
| Ryoutarou Okiayu | Byakuya Kuchiki |
| Fumihiko Tachiki | Kenpachi Zaraki |
| Hisayo Mochizuki | Yachiru |
| Akio Ohtsuka | Shunsui Kyouraku |
| Kumi Sakuma | Momo Hinamori |
| Romi Paku | Toushirou Hitsugaya |
| Kouki Miyata | Hanatarou Yamada |
| Shou Hayami | Sousuke Aizen |
| Hideo Ishikawa | Juushirou Ukitake |
| Asami Sanada | Michiru Ogawa |
| Saki Nakajima | Chizuru Honshou |
| Kiyoyuki Yanada | Tessai Tsukabishi |
| Takako Honda | Jinta Hanakari |
| Noriko Shitaya | Ururu Tsumugiya |
| Katsuyuki Konishi | Shuuhei Hisagi |
| Wataru Takagi | Ganju Shiba |
| Masaaki Tsukada | Yamamoto Genryuusai Shigekuni |
| Ryusei Nakao | Mayuri Kurotsuchi |
| Toshiyuki Morikawa | Kaname Tousen |
| Tomoko Kawakami | Soi Fong |
| Kaya Matsutani | Rangiku Matsumoto |
| Takahiro Sakurai | Izuru Kira |
| Nobuyuki Hiyama | Ikkaku Madarame |
| Jun Fukuyama | Yumichika Ayasegawa |
| Hitomi Nabatame | Nanao Ise |
| Kouichi Tohchika | Sentarou Kotsubaki |
| Satsuki Yukino | Yoruichi Shihouin |
| Tetsu Inada | Sajin Komamura |
| Yumi Kakazu | Ririn (Episode 64 - 77, 79) |
| Nobuo Tobita | Kuroudo (Episode 65 - 77, 79) |
| Tomokazu Sugita | Noba (Episode 65, 66, 69 - 77, 79) |
| Masako Katsuki | Yoshino Souma |
| Toru Ohkawa | Jin Kariya (Episode 70 - 79) |
| Masaya Onosaka | Shinji Hirako |
| Junichi Suwabe | Grimmjow |
| Daisuke Namikawa | Ulquiorra |
| Kenji Nomura | Yammy |
| Akemi Kanda | Mashiro |
| Reiko Takagi | Hiyori Sarugaki |
| Tetsu Inada | Love |
| Shouto Kashii | Rose |
| Takashi Nagasako | Hachigen Ushouda |
| Tomokazu Sugita | Kensei Muguruma |
| Yuuji Ueda | Orihime's Brother (Episode 2, 3, 13, 64) |
| Furin Cha | Grand Fisher (Episode 2, 4, 8, 9) |
| Sayaka Ohara | Ichigo's Mother (Episode 8 & 9) |
| Makoto Tsumura | Yuuichi Shibata (Episode 4, 5, 22) |
| Shigeru Chiba | Don Kanonji (Episode 10, 50, 54, 55) |
| Kazuhiro Nakata | Kagine-sensei (Episode 11 & 67) |
| Eiji Maruyama | Souken Ishida (Episode 14, 44, 45) |
| Junko Noda | Shunou (Episode 13, 19, 22, 30, 43) |
| Toshiyuki Morikawa | Tsubaki (Episode 13, 19, 28, 29, 43) |
| Daisuke Kishio | Hinagiku (Episode 13, 19, 43) |
| Rie Kugimiya | Lily (Episode 13 & 19) |
| Tomoe Sakuragawa | Ayame (Episode 13, 19, 22, 30) |
| Takayuki Sugou | Zangetsu |
| Asami Sanada | Kanisawa (Episode 46) |
| Takashi Nagasako | Jidanbou (Episode 21, 22, 56, 62) |
| Mayumi Asano | Hironari Horiuchi (Episode 22) |
| Hiroshi Matsumoto | Koganehiko (Episode 23 - 25) |
| Kenta Miyake | Shiroganehiko (Episode 23 - 25) |
| Akiko Hiramatsu | Kuukaku Shiba (Episode 23 - 25, 56, 62, 63) |
| Rie Kugimiya | Nemu Kurotsuchi (Episode 28, 29, 43, 44, 61, 78) |
| Kazuhiro Nakata | Jiroubou Ikkanzaka (Episode 28 & 29) |
| Shouto Kashii | Marechiyo Oomaeda (Episode 30, 51 - 55, 62) |
| Reiko Kiuchi | Renji (as a child Episode 32) |
| Aya Hisakawa | Retsu Unohana (Episode 38, 45, 54, 55, 60 - 63) |
| Chinami Nishimura | Kiyone Kotetsu |
| Toru Furusawa | Zabimaru (Episode 42) |
| Yuichi Nagashima | Makizou Aramaki |
| Kiyoyuki Yanada | Baigon |
| Takako Honda | Uryuu (as a child Episode 43 & 44) |
| Ken Narita | Uryuu's Father (Episode 44) |
| Yukana Nogami | Isane Kotetsu (Episode 45, 54, 55, 60, 61, 63) |
| Toshihiko Seki | Kaien Shiba (Episode 49) |
| Sumi Shimamoto | Miyako Shiba (Episode 49) |
| Daisuke Sakaguchi | Hou & Ban (Episode 72 - 74) |
| Susumu Chiba | Maki Ichinose (Episode 73 - 79) |
| Toru Furusawa | Koga (Episode 73 - 77, 79) |
| Daisuke Ono | Mabashi (Episode 73 - 76) |
| Yoko Soumi | Yoshi (Episode 75 & 76) |
| Takako Honda | Dark (Episode 75, 76, 79) |
| Kaoru Morota | Mizuho Asano |
| Reiko Takagi | Shouta Toyokawa |
| Yurika Ochiai | Shouta's Sister |
| Hideyuki Tanaka | Shawlong |
| Kouichi Tohchika | Ilfort |
| Taiten Kusunoki | Edorad |
| Takashi Kondou | D-Roy |
| Taeko Kawata | Miyuki |